Oncology Department
Dernière mise à jour :
The CIC-P's oncology sites provide expertise in developing et conducting early-phase studies, with CLIP2 (early-phase clinical trials centre) label.
Research Unit
- Unité Inserm U1029 (LAMC : Laboratoire de l'Angiogenèse et du Micro-environnement des Cancers) directed by Professor A. Bikfalvi
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Inserm U916 Unit (VINCO : Validation and Identification of New Targets in Oncology) directed by Prof. P. Soubeyran
Head of Department
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Prof. Pierre Soubeyran (Bergonié Institute) — Dr. Pierre-Yves Dumas (University Hospital of Bordeaux)
Research Themes
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Onco-hematology
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Therapeutic adaptation
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Early phase and post-approval studies
Academic reputation and attractiveness
Labelling
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2015: INCa CLIP2 Label (Dr. Italiano)
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2012: SIRIC BRIO (Prof. Soubeyran)
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2010: CRC (Clinical Research Center) Label (Bergonié Institute)
Other actions
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2014: 1st Bordeaux Meeting on Bioinformatics of personalized treatment of cancer (June 20, 2014)
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European Preceptorship of the oncology service (Prof. A. Ravaud) in association with the imagery service (Prof. N. Grenier, Dr. F. Cornelis) and urology surgery (Dr. JC Bernhard) on kidney cancer including a major part on angiogenesis (3 sessions in 2014)
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2014: INSERM funding for leiomyosarcoma sequencing in the context of the International Cancer Genome Consortium, ICGC (F. Chibon).
Interactions with the socioeconomic and cultural environment
University Hospital of bordeaux
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Industrial partnership for the realization of Phase I academic clinical trials
Bergonie Institute
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Partnership with the association of the “Info Sarcomes” patients (“Ensemble contre les Sarcomes”)
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May 23rd, 2014: Open day of the INSERM U916 Unit, Genetic, and Sarcoma Biology team (INSERM, Bergonié Institute, University of Bordeaux)
Contribution to training
University Hospital of BOrdeaux
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Training grounds for interns in Specialized Studies Diploma (DES) in medical oncology
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Training grounds for CRAs (Clinical Research associate) in training
Bergonie institute
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Since 2011,the ATRIVM training group has been providing training activities in oncology for doctors and other healthcare professionals
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Following its registration to the ANDPC (Agence Nationale du Développement Professionnel Continu), the Bergonié Institute was habilitated in 2013 to provide programs of CPD (Continuing Professional Development)
Main publication in recent years
University Hospital of Bordeaux
- Ravaud A, Gomez-Roca C, Picat MQ, Digue L, Chevreau C, Gimbert A, Chauzit E, Sitta R, Cornelis F, Asselineau J, Aziza R, Daste A, Quemener C, Baud J, Bikfalvi A, Pedenon-Périchout D, Doussau A, Molimard M, Delord JP. Phase I study of axitinib and everolimus in metastatic solid tumours and extension to metastatic renal cell carcinoma: Results of EVAX study. Eur J Cancer. 2017 Nov;85:39-48
- Ravaud A, Schmidinger M. Clinical biomarkers of response in advanced renal cell carcinoma. Ann Oncol. 2013 Dec;24(12):2935-42
- Ravaud A, Gross-Goupil M. Overcoming resistance to tyrosine kinase inhibitors in renal cell carcinoma. Cancer Treat Rev. 2012 Feb 11
- Ravaud A, de la Fouchardière C, Asselineau J, Delord JP, Do Cao C, Niccoli P, Rodien P, Klein M, Catargi B. Efficacy of sunitinib in advanced medullary thyroid carcinoma: intermediate results of phase II THYSU. Oncologist 2010 ; 15 : 212-3
- Motzer RJ, Escudier B, Oudard S, Hutson TE, Porta C, Bracarda S, Grünwald V, Thompson JA, Figlin RA, Hollaender N, Urbanowitz G, Berg WJ, Kay A, Lebwohl D, Ravaud A, RECORD-1 Study Group. Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial. Lancet 2008 Aug 9;372(9637):449-56
Bergonie Institute
- Meynard L, Dinart D, Delaunay B, Fléchon A, Saldana C, Lefort F, Gravis G, Thiery-Vuillemin A, Cancel M, Coquan E, Ladoire S, Maillet D, Rolland F, Boughalem E, Martin S, Laramas M, Crouzet L, Abbar B, Falkowski S, Pouessel D, Roubaud G. Chemotherapy following immune checkpoint inhibitors in patients with locally advanced or metastatic urothelial carcinoma. Eur J Cancer. 2022 Nov;175:43-53.DOI:10.1016/j.ejca.2022.08.014
- Bayle A, Peyraud F, Belcaid L, Brunet M, Aldea M, Clodion R, Dubos P, Vasseur D, Nicotra C, Geraud A, Sakkal M, Cerbone L, Blanc-Durand F, Mosele F, Martin Romano P, Ngo Camus M, Soubeyran I, Khalifa E, Alame M, Blouin L, Dinart D, Bellera C, Hollebecque A, Ponce S, Loriot Y, Besse B, Lacroix L, Rouleau E, Barlesi F, Andre F, Italiano A. Liquid versus tissue biopsy for detecting actionable alterations according to the ESMO Scale for Clinical Actionability of molecular Targets in patients with advanced cancer: a study from the French National Center for Precision Medicine (PRISM). Ann Oncol. 2022 Dec;33(12):1328-1331. DOI:10.1016/j.annonc.2022.08.089
- Amadeo B, Penel N, Coindre JM, Ray-Coquard I, Plouvier S, Delafosse P, Bouvier AM, Gallet J, Lacourt A, Galvin A, Coureau G, Monnereau A, Blay JY, Desandes E, Mathoulin-Pélissier S; French Network of Cancer Registries (FRANCIM). Overall and net survival of patients with sarcoma between 2005 and 2010: Results from the French Network of Cancer Registries (FRANCIM). Cancer. 2022 Jul 1;128(13):2483-2492. DOI:10.1002/cncr.34217
Search for volunteers for ongoing studies.
No current search for volunteers
Contact
- Clinical Research Coordinator : Delphine Pedenon-Peyrichout
delphine.pedenon%40chu-bordeaux.fr
delphine.pedenon%40chu-bordeaux.fr
05 56 79 47 08